first. PNplus stands for Peace and Protection Plus..from the word itself it should protect users from any disturbances not like this case,from the word itself,well,anyways,nobody's software's perfect
second,there are commands that wont work in the older version of PnP,please check if you have the latest one. The updates contain much needed bug fixes as well as modification to help make the mirc experience more enjoyable
third,quoted from a site of PnPlus: "it is recommended that you wait until we have had the chance to test the new "mirc in pnplus". The reason for this being that there could be conflicts between mirc and p&plus.
fourth,maybe you load P&plus twice from the same folder. If you need to run to copies of p&plus, install it to another folder.That will prevent errors
fifth,the common method "close and reopen"
sixth,i advise you to uninstall then read the faq first before trying to install it again. There are a lot of site regarding Pnplus, regarding vital information and problem solving technique
lastly,just shout me in #beginner if i misunderstood your problem.